Simulating Mutation and Selection

This app allows you to simulate the combined effects of mutation and natural selection on the frequency of an allele A (p). Critical parameters include:

• The starting allele frequency, p0. This parameter can vary between 0 and 1.

• The relative fitness of genotypes Aa and aa (note that the fitness of AA is fixed at 1). Fitness values can vary between 0 and 2.

• The mutation rate from A to a, which can vary from 0.00001 to 1.

• The number of generations you want to run the simulation for (maximum: 1000).

Try to play with different scenarios. Change one parameter at a time to explore how outcomes vary.

To access the app directly, click here. This app is based on the learnPopGen package by Liam Revell.